CSTF3 Polyclonal Antibody

CAT: 0498-bs-12935RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-12935RSize:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors. The first step, endonucleolytic cleavage of polyadenylation substrates, requires CstF (cleavage stimulation factor), a heterotrimer that is composed of three distinct subunits. Heterotrimeric CstF recognizes GU- and U-rich sequences located downstream of the polyadenylation site on RNA. CstF-77 (cleavage stimulation factor, 77 kDa subunit), also known as CstF3, is one of the three subunits comprising CstF. It can exist as a homodimer and functions as the bridge, directly interacting with the other two CstF subunits, namely CstF-64 and CstF-50. CstF-77 is highly conserved among eukaryotes. It contains an Alpha-helical structure with 11 HAT (Half-a-TPR-containing) repeats and is essential for CstF assembly. In addition, CstF-77 is capable of interacting with CPSF1 and FCP1, other factors involved in polyadenylation.
Synonyms
CF 1 77 kDa subunit; Cleavage stimulation factor 77 kDa subunit; Cleavage stimulation factor subunit 3; Cleavage stimulation factor subunit 3 isoform 1; CSTF 3; CSTF 77; CSTF 77 kDa subunit; CSTF77; MGC117398; MGC43001; MGC75122; CSTF3_HUMAN.
Gene ID
1479
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
151-250/717
Target
CSTF3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CSTF3/CSTF77
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
1479
Predicted Cross Reactivity
Human, Rat, Dog, Cow, Chicken, Rabbit

Related Products

CatalogName
bs-6995RCstF-64 Polyclonal Antibody
bs-6995R-PerCPCstF-64 Polyclonal Antibody, PerCP Conjugated
bs-6995R-APCCstF-64 Polyclonal Antibody, APC Conjugated
bs-6995R-Cy3CstF-64 Polyclonal Antibody, Cy3 Conjugated
bs-6995R-Cy5CstF-64 Polyclonal Antibody, Cy5 Conjugated
bs-6995R-FITCCstF-64 Polyclonal Antibody, FITC Conjugated
bs-6995R-HRPCstF-64 Polyclonal Antibody, HRP Conjugated
bs-6995R-Cy7CstF-64 Polyclonal Antibody, Cy7 Conjugated
bs-6995R-PECstF-64 Polyclonal Antibody, PE Conjugated
bs-6995R-RBITCCstF-64 Polyclonal Antibody, RBITC Conjugated

Alternative Products

CatalogName
MBS2560986-01CSTF3 Polyclonal Antibody
TA345770CSTF3 Rabbit Polyclonal Antibody
AP32732PU-NCSTF3 Goat Polyclonal Antibody
NBP1-85427-25ulRabbit Polyclonal CSTF3 Antibody
MF-0071540-01Anti-CSTF3 Polyclonal Antibody
PAV6373Rabbit Anti-CSTF3 Polyclonal Antibody
MBS8108472-01Anti-CSTF-77/CSTF3 Antibody, Rabbit Polyclonal
DF14656-01CSTF3 Antibody

Popular Products