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LY 345899

CAT: 0957-E1317Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E1317Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY345899 is a Folate analog and a potent inbhibitor of methylene tetrahydrofolate dehydrogenase1 (MTHFD1; DC301) and methylene tetrahydrofolate dehydrogenase2 (MTHFD2) with IC50 values of 96 nM and 663 nM, respectively. It significantly suppresses tumor growth and reduces tumor weight in CRC patient-derived xenograft models.
CAS Number
10538-99-5
Target
Others
Activity
Others
Molecular Formula
C20H21N7O7

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Alternative Products

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GTR19156922-01LY 345899
A19440-25LY 345899 25mg
A19440-10LY 345899 10mg
A19440-1LY 345899 1mg
A19440-500LY 345899 500mg
A19440-100LY 345899 100mg
A19440-50LY 345899 50mg
A19440-5LY 345899 5mg
A19440-10mM-DLY 345899 10mM * 1mL in DMSO

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