VPS45A Polyclonal Antibody

• Background :

  Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]

• Synonyms :

  H-VPS45; H1; H1VPS45; HGNC:14579; hlVps45; Leucocyte vacuolar protein sorting 45; OTTHUMP00000014482; Vacuolar protein sorting 45 homolog (S. cerevisiae) ; Vacuolar protein sorting 45A (yeast homolog) ; Vacuolar protein sorting 45A; Vacuolar protein sorting 45B (yeast) ; Vacuolar protein sorting-associated protein 45; VPS45; VPS45_HUMAN; VPS45A; VPS45B; VPS54A; VSP45; VSP45A.

• Gene ID :

  11311

• Swiss Prot :

  Q9NRW7

• Cellular Locus :

  Cytoplasm, Cell membrane

• Host :

  Rabbit

• Cross Reactivity :

  Mouse

• Immunogen :

  401-500/570

• Target :

  VPS45A

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human VPS45A

• Applications :

  IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  11311

• Predicted Cross Reactivity :

  Human, Rat, Dog, Cow, Sheep, Pig, Horse