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E1231

CAT: 0957-E6484-04Size: 1 gDry Ice: NoHazardous: No
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CAT#:0957-E6484-04Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
E1231 (1-{4-[2- (5-Methylfuran-2-yl) quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one) is a piperazine 1,4-diamide compound and an oral activator of SIRT1 with an EC50 of 0.83μM. It increases cholesterol efflux and decreases lipid accumulation in macrophages. E1231 regulates cholesterol and lipid metabolism in hyperlipidemic golden hamsters, with potential for atherosclerosis treatment.
CAS Number
1031195-19-3
Synonyms
1-{4-[2- (5-Methylfuran-2-yl) quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one
Target
Survivin
Activity
Apoptosis
Molecular Formula
C21H21N3O3

Alternative Products

CatalogName
BA4514-25E1231

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