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Motixafortide (BL-8040)

CAT: 0957-S9665-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S9665-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Motixafortide (BL-8040, BKT140, TF 14016, 4-fluorobenzoyl, 4F-benzoyl-TN14003, T140) is an antagonist of CXCR4 with IC50 of ~1 nM. BL-8040 induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.
CAS Number
664334-36-5
Synonyms
BKT140, TF 14016, 4-fluorobenzoyl, 4F-benzoyl-TN14003, T140
Target
CXCR
Activity
GPCR & G Protein
Molecular Formula
C97H144FN33O19S2
Storage Conditions
3 years -20°C powder