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VPREB1 Polyclonal Antibody

CAT: 0498-bs-12326R-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-12326R-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
VpreB is expressed in pre-B lymphocytes, but not in mature B cells or in other blood cell lineages. The gene which encodes VpreB maps to human chromosome 22q11.2. The VpreB and Lambda 5 genes encode the Iota and Omega polypeptide chains, respectively, which associate with the Ig-Mu chain to form a molecular complex that is expressed on the surface of pre-B cells. This complex presumably regulates Ig gene rearrangements in the early steps of B cell differentiation. In the mouse the two genes are simultaneously expressed in pre-B cells and belong to the same transcription unit. A primary transcript is synthesized from which the pre-B and Lambda 5 mRNAs are derived by alternative splicing. In the human, however, the two genes are separate and do not belong to the same transcription unit.
Synonyms
CD179 antigen like family member A; CD179 antigen-like family member A; CD179a; IGI; IGVPB; Immunoglobulin iota chain; Pre B lymphocyte 1; pre-B lymphocyte 1; Protein VPreB1; VpreB protein; VPREB 1; VPREB; VpreB protein; VPREB_HUMAN; VPREB1.
Gene ID
7441
Cellular Locus
Extracellular matrix
Host
Rabbit
Immunogen
61-145/145
Target
VPREB1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human VPREB1/CD179a
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
7441
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Sheep, Pig, Horse, Rabbit

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