LRRC23 Polyclonal Antibody

CAT: 0498-bs-12311RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-12311RSize:100 µL
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Background
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å / horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC23 (leucine-rich repeat-containing protein 23), also known as leucine-rich protein B7, is a 343 amino acid protein that contains eight LRR (leucine-rich) repeasts and one LRRCT domain. LRRC23 exists as two alternatively spliced isoforms and is encoded by a gene mapping to chromosome 12.
Synonyms
Leucine rich protein B7; Leucine rich repeat containing 23; Leucine rich repeat containing protein 23; Lrpb7; LRC23_HUMAN.
Gene ID
10233
Cellular Locus
Nucleus
Host
Rabbit
Immunogen
251-343/343
Target
LRRC23
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human LRRC23
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
10233
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Sheep, Horse, Rabbit

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