MSY2 Polyclonal Antibody

CAT: 0498-bs-12271RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-12271RSize:100 µL
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Background
MSY2 and YB-2 (MSY3,4) belong to the Y-box family of multifunctional proteins that regulate both transcription and translation (13) . Y-box proteins interact with a wide variety of nucleic acid structures to act as transcription factors and mRNA masking proteins (1) . The modular structure of Y-box proteins includes a highly conserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shock proteins) and four basic C-terminal domains containing arginine clusters and aromatic residues (4) . MSY2 is expressed in testis and ovary where it may repress translation of parental mRNA (5,6) . The gene encoding human MSY2 maps to chromosome 17p11.2-13.1 (5) . YB-2 (MSY3,4 in mouse) is also known as DNA binding protein A and is highly expressed in the testis, heart and muscle (7,8) . MSY2 and YB-2 bind to the consensus sequence 5'-UCCAUCA-3' contained in the Y-box element (9) .
Synonyms
Contrin; CSDA 3; CSDA3; DBPC; DNA binding protein C; DNA-binding protein C; FRGY2 homolog; Germ cell specic Y box binding protein; Germ cell-specic Y-box-binding protein; MGC118270; MGC45104; MSY 2; MSY2; MSY2 homolog; OTTMUSP00000006276; RGD1305068; Y box binding protein 2; Y-box-binding protein 2; YBOX2_HUMAN; YBX 2; YBX2.
Gene ID
51087
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Immunogen
101-185/364
Target
MSY2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human YBOX2
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
51087
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse

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