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ZNF274 Polyclonal Antibody

CAT: 0498-bs-12209RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-12209RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. A member of the Kr_ppel C2H2-type zinc-finger protein family, ZNF274, also known as Zinc finger protein with KRAB and SCAN domains 19, is a 653 amino acid protein containing five C2H2-type zinc fingers, two KRAB A domains and one SCAN box domain. Predominantly localized to the nucleolus, ZNF274 exhibits transcriptional repressing activity. There are four isoforms of ZNF274 that are produced as a result of alternative splicing events. Although total ZNF274 expression seems to be ubiquitous, the two main isoforms, ZNF274a and ZNF274b, differ slightly in tissue distribution with higher expression of ZNF274a in testis and higher expression of ZNF274b in spleen, ovary, skeletal muscle and thymus.
Synonyms
SP2114; Zf2; Zinc finger protein 274; Zinc finger protein HFB101; Zinc finger protein with KRAB and SCAN domains 19; Zinc finger protein zfp2; ZKSCAN19; ZN274_HUMAN.
Gene ID
10782
Cellular Locus
Nucleus
Host
Rabbit
Immunogen
251-350/653
Target
ZNF274
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ZNF274
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
10782
Predicted Cross Reactivity
Human, Mouse, Rat, Rabbit