Products for Research Use Only
RegisterLogin

NPS-2143

CAT: 0957-S2633-01Size: 10 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0957-S2633-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NPS-2143 (SB262470) is a novel potent and selective antagonist of Ca (2+) receptor with IC50 of 43 nM.
CAS Number
284035-33-2
Synonyms
SB262470
Target
CaSR
Activity
GPCR & G Protein
Molecular Formula
C24H25ClN2O2
Storage Conditions
2 years -80 in solvent

Chemical Information

Nps-2143
CAS Number284035-33-2
PubChem CID6918446
IUPAC Name2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile
Molecular FormulaC24H25ClN2O2
Molecular Weight408.9
XLogP5
Topological Polar Surface Area65.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count8
Heavy Atom Count29
Formal Charge0
Complexity560
SMILES
CC(C)(CC1=CC2=CC=CC=C2C=C1)NC[C@H](COC3=C(C(=CC=C3)Cl)C#N)O
InChI
InChI=1S/C24H25ClN2O2/c1-24(2,13-17-10-11-18-6-3-4-7-19(18)12-17)27-15-20(28)16-29-23-9-5-8-22(25)21(23)14-26/h3-12,20,27-28H,13,15-16H2,1-2H3/t20-/m1/s1
InChIKey
PZUJQWHTIRWCID-HXUWFJFHSA-N
Chemical Structure
2D Structure
2D structure of Nps-2143
CAS: 284035-33-2
CID: 6918446
Formula: C24H25ClN2O2
MW: 408.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight408.9
XLogP35
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count8
Exact Mass408.1604557
Monoisotopic Mass408.1604557
Topological Polar Surface Area65.3 Ų
Heavy Atom Count29
Formal Charge0
Complexity560
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
S7669-100mgNPS-1034
S7669-5mgNPS-1034
S7669-25mgNPS-1034
S7669-01NPS-1034
A01290-1Anti-Neuropeptide S/NPS Antibody
E1966-1gVVD-214
E1966-25mgVVD-214
E1966-5mgVVD-214
S1485-10mgHMN-214
S1485-01HMN-214

Alternative Products

CatalogName
MBS8506335-01NPS-2143
460973-01NPS 2143
A3667-200NPS-2143 hydrochloride
HY-10007RNPS-2143 (Standard)
3626/50NPS 2143 hydrochloride
A11140-200NPS-2143 200mg
HY-10171-01NPS-2143 (hydrochloride)
526760NPS-2143 HCl

Popular Products