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Amarogentin

CAT: 0957-S1273-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S1273-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Amarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin is an agonist for the bitter taste receptor TAS2R1 and inhibits in LAD-2 cells substance P-induced production of newly synthesized TNF-α. Amarogentin induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway. Amarogentin (AG) interacts with the α2 subunit of AMP-activated protein kinase (AMPK) and activates the trimeric kinase with EC50 of 277 pM.
CAS Number
21018-84-8
Synonyms
AG
Target
Taste Receptor
Activity
GPCR & G Protein
Molecular Formula
C29H30O13
Storage Conditions
3 years -20°C powder

Alternative Products

CatalogName
TBZ1093Amarogentin
A22286-50Amarogentin 50mg
A22286-25Amarogentin 25mg
A22286-5Amarogentin 5mg
HY-N2447R-01Amarogentin (Standard)
A22286-100Amarogentin 100mg
A22286-10Amarogentin 10mg
A22286-2Amarogentin 2mg

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