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SR-717 lithium

CAT: 0957-S0853-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S0853-01Size:5 mg
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Description
SR-717 lithium is a non-nucleotide STING agonist that demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 (cGAS KO) cell lines, respectively. SR-717 lithium also induces the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. SR-717 lithium exhibits antitumor activity.
CAS Number
2375421-09-1
Target
STING
Activity
Immunology & Inflammation
Molecular Formula
C15H8F2LiN5O3
Storage Conditions
3 years -20°C powder

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