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BI-671800

CAT: 0957-S0495-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S0495-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BI-671800 (AP-761, Cmpd A) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) with IC50 of 4.5 nM and 3.7 nM for PGD2 binding to human CRTH2 and murine CRTH2, respectively. BI-671800 is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in patients on ICS.
CAS Number
1093108-50-9
Synonyms
AP-761, Cmpd A
Target
Prostaglandin Receptor
Activity
GPCR & G Protein
Molecular Formula
C25H26F3N5O3
Storage Conditions
3 years -20°C powder