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HSF1A

CAT: 0957-S0294-03Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0957-S0294-03Size:100 mg
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Description
HSF1A is a cell-permeable heat shock transcription factor 1 (HSF1) activator. HSF1A protects cells from stress-induced apoptosis, binds TRiC subunits and inhibits TRiC activity without perturbation of ATP hydrolysis.
CAS Number
1196723-93-9
Target
HSP (HSP90)
Activity
Cytoskeletal Signaling
Molecular Formula
C21H19N3O2S2
Storage Conditions
3 years -20°C powder

Chemical Information

4-Ethyl-N-(1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-5-yl)benzenesulfonamide
CAS Number1196723-93-9
PubChem CID44472508
IUPAC Name4-ethyl-N-(1-phenyl-3-thiophen-2-ylpyrazol-5-yl)benzenesulfonamide
Molecular FormulaC21H19N3O2S2
Molecular Weight409.5
XLogP4.9
Topological Polar Surface Area101
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count28
Formal Charge0
Complexity595
SMILES
CCC1=CC=C(C=C1)S(=O)(=O)NC2=CC(=NN2C3=CC=CC=C3)C4=CC=CS4
InChI
InChI=1S/C21H19N3O2S2/c1-2-16-10-12-18(13-11-16)28(25,26)23-21-15-19(20-9-6-14-27-20)22-24(21)17-7-4-3-5-8-17/h3-15,23H,2H2,1H3
InChIKey
KJTITGSAONQVPY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-Ethyl-N-(1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-5-yl)benzenesulfonamide
CAS: 1196723-93-9
CID: 44472508
Formula: C21H19N3O2S2
MW: 409.5
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight409.5
XLogP34.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass409.09186920
Monoisotopic Mass409.09186920
Topological Polar Surface Area101 Ų
Heavy Atom Count28
Formal Charge0
Complexity595
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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