GPR116 Polyclonal Antibody

CAT: 0498-bs-12025RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-12025RSize:100 µL
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AVAILABILITY: InStock
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Background
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein that contains one SEA domain, one GPS domain and three Ig-like domains and belongs to the GPR family. Existing as a dilsulfide-liked homodimer at the cell surface, GPR116 exists as multiple alternatively spliced isoforms and is thought to play a role in regulating and maintaining proper acid-base balance throughout the cell.
Synonyms
DKFZp564O1923; FLJ90640; G protein coupled receptor 116; G protein coupled receptor 116; GP116_HUMAN; GPR116; Ig Hepta homolog; KIAA0758; KIAA0758; KPG_001; OTTHUMP00000016557; Probable G protein coupled receptor 116; Probable G-protein coupled receptor 116_ GPCR GPR116.
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
501-600/1346
Target
GPR116
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human G protein coupled receptor 116
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Predicted Cross Reactivity
Human, Mouse, Rat, Rabbit

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