Products for Research Use Only
RegisterLogin

TNF-α (31-45), human

CAT: 0957-E7641Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-E7641Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TNF-α (31-45), human is a potent activator of NF-kB pathway. It is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and is responsible for a diverse range of signalling events within cells, leading to necrosis or apoptosis. It can be used in research of autoimmune diseases.
CAS Number
144796-71-4
Target
NF-κB
Activity
NF-κB
Molecular Formula
C69H122N26O22

Chemical Information

H-Arg-arg-ala-asn-ala-leu-leu-ala-asn-gly-val-glu-leu-arg-asp-OH
CAS Number144796-71-4
PubChem CID71311650
IUPAC Name(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-4-oxobutanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-4-carboxybutanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]butanedioic acid
Molecular FormulaC69H122N26O22
Molecular Weight1667.9
XLogP-10
Topological Polar Surface Area825
Hydrogen Bond Donor Count26
Hydrogen Bond Acceptor Count26
Rotatable Bond Count57
Heavy Atom Count117
Formal Charge0
Complexity3550
SMILES
C[C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)N
InChI
InChI=1S/C69H122N26O22/c1-30(2)23-41(93-64(114)42(24-31(3)4)89-53(103)35(10)85-62(112)45(27-48(72)97)91-55(105)34(9)83-58(108)38(16-13-21-80-68(75)76)86-56(106)37(70)15-12-20-79-67(73)74)61(111)84-36(11)54(104)90-44(26-47(71)96)57(107)82-29-49(98)95-52(33(7)8)65(115)88-40(18-19-50(99)100)60(110)92-43(25-32(5)6)63(113)87-39(17-14-22-81-69(77)78)59(109)94-46(66(116)117)28-51(101)102/h30-46,52H,12-29,70H2,1-11H3,(H2,71,96)(H2,72,97)(H,82,107)(H,83,108)(H,84,111)(H,85,112)(H,86,106)(H,87,113)(H,88,115)(H,89,103)(H,90,104)(H,91,105)(H,92,110)(H,93,114)(H,94,109)(H,95,98)(H,99,100)(H,101,102)(H,116,117)(H4,73,74,79)(H4,75,76,80)(H4,77,78,81)/t34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,52-/m0/s1
InChIKey
HYFATHUJEOQTRM-PJKQPBPGSA-N
Chemical Structure
2D Structure
2D structure of H-Arg-arg-ala-asn-ala-leu-leu-ala-asn-gly-val-glu-leu-arg-asp-OH
CAS: 144796-71-4
CID: 71311650
Formula: C69H122N26O22
MW: 1667.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1667.9
XLogP3-10
Hydrogen Bond Donor Count26
Hydrogen Bond Acceptor Count26
Rotatable Bond Count57
Exact Mass1666.92269963
Monoisotopic Mass1666.92269963
Topological Polar Surface Area825 Ų
Heavy Atom Count117
Formal Charge0
Complexity3550
Isotope Atom Count0
Defined Atom Stereocenter Count14
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
EK0979Human IL-31/Interleukin-31 ELISA Kit PicoKine®
S3493-5mgAPS6-45
S3493-01APS6-45
S3493-25mgAPS6-45
S9848-01LM11A-31
E6697-01PACMA 31
E0115-5mgMTI-31
S7931-25mgSTF-31
S0311-5mgSKA-31
S0311-25mgSKA-31

Alternative Products

CatalogName
M41706-01TNF-α (31-45), human
T76026-01TNF-α (31-45), human TFA
HY-P1860A-01TNF-α (31-45), human (TFA)
MBS8247095-01TNF-Alpha (31-45) (Human)
5-02009TNF - alfa (31 - 45), human
T19584L-01TNF-α (31-45), human acetate
MBS5772054TNF-alpha (31-45), Human
PE-86636-01TNF-Alpha (31-45) Human Peptide
GTR18891132Human TNF alpha (31-45) peptide
A22784-10TNF-α (31-45), human 10mg

Popular Products