Products for Research Use Only
RegisterLogin

Tafluprost acid

CAT: 0957-E7166Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-E7166Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Tafluprost acid (AFP-172), the active metabolite of Tafluprost, is a selective agonist of the prostanoid FP receptor, with Ki and IC50 of 0.4 nM and 0.53 nM, respectively, for the human prostanoid FP receptor. It also exhibits 126-fold weaker binding affinity for the prostanoid EP3 receptor, with an IC50 of 67 nM, compared to the FP receptor.
CAS Number
209860-88-8
Synonyms
AFP-172
Molecular Formula
C22H28F2O5
Storage Conditions
2 years -20°C liquid

Chemical Information

Tafluprost acid
CAS Number209860-88-8
PubChem CID9978917
IUPAC Name(Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid
Molecular FormulaC22H28F2O5
Molecular Weight410.5
XLogP3.3
Topological Polar Surface Area87
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count11
Heavy Atom Count29
Formal Charge0
Complexity557
SMILES
C1[C@@H]([C@@H]([C@H]([C@@H]1O)/C=C/C(COC2=CC=CC=C2)(F)F)C/C=C\CCCC(=O)O)O
InChI
InChI=1S/C22H28F2O5/c23-22(24,15-29-16-8-4-3-5-9-16)13-12-18-17(19(25)14-20(18)26)10-6-1-2-7-11-21(27)28/h1,3-6,8-9,12-13,17-20,25-26H,2,7,10-11,14-15H2,(H,27,28)/b6-1-,13-12+/t17-,18-,19+,20-/m1/s1
InChIKey
KIQXRQVVYTYYAZ-VKVYFNERSA-N
Chemical Structure
2D Structure
2D structure of Tafluprost acid
CAS: 209860-88-8
CID: 9978917
Formula: C22H28F2O5
MW: 410.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight410.5
XLogP33.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count11
Exact Mass410.19048031
Monoisotopic Mass410.19048031
Topological Polar Surface Area87 Ų
Heavy Atom Count29
Formal Charge0
Complexity557
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
S4851-2mgTafluprost
S4851-5mgTafluprost
S4851-01Tafluprost
E0518-5mgPolyinosinic acid-polycytidylic acid
E0518-01Polyinosinic acid-polycytidylic acid
E0518-25mgPolyinosinic acid-polycytidylic acid
E7976-5mgAsparagusic acid
E7823Guluronic acid
E7810-5mgEicosadienoic acid
E7490-1mgMeclofenamic acid

Alternative Products

CatalogName
HY-B0601-01Tafluprost acid
HY-B0601RTafluprost acid (Standard)
sc-205516Tafluprost (free acid)
466788-01Tafluprost Acid-d4
TRC-T004820-1MGTafluprost

Popular Products