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HES6 Polyclonal Antibody

CAT: 0498-bs-11852RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-11852RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation (By similarity) .
Synonyms
HES-6; bHLHb41; bHLHc23; C-HAIRY1; Transcription cofactor HES-6; Class B basic helix-loop-helix protein 41; Hairy and enhancer of split 6; HES6
Gene ID
55502
Swiss Prot
Q96HZ4
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
1-80/224
Target
HES6
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human HES6
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
55502
Predicted Cross Reactivity
Mouse, Rat, Cow, Pig