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W-54011

CAT: 0957-E2857Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0957-E2857Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
W-54011 is a potent and orally active non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM. W-54011 also inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophils with IC50s of 3.1 nM, 2.7 nM, and 1.6 nM, respectively.
CAS Number
405098-33-1
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent

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