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UNC6934

CAT: 0957-E1059-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E1059-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UNC6934 is a a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2. UNC6934 is a potent antagonist of NSD2-PWWP1 with a Kd (SPR) of 80 nM and is selective for NSD2-PWWP1 over 14 other PWWP domains including NSD3-PWWP1 UNC6934 disrupts the NSD2-PWWP1 interaction with H3K36me2 nucleosomes in U2OS cells as measured by a NanoBret assay with an IC50 of 1.09 μM.
CAS Number
2561494-77-5
Target
NSD
Activity
Epigenetics
Molecular Formula
C24H21N5O4
Storage Conditions
3 years -20°C powder

Alternative Products

CatalogName
BUP07932-01UNC6934
A24331-100UNC6934 100mg
A24331-10UNC6934 10mg
A24331-50UNC6934 50mg
A24331-5UNC6934 5mg

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