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Naperiglipron

CAT: 0957-E6560-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E6560-01Size:5 mg
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Description
Naperiglipron (LY3549492) (Example 2) acts as a glucagon-like peptide 1 receptor (GLP-1R) agonist, exhibiting an EC50 of 1.14 nM at hGLP-1R. In GLP-1R knock-in mouse models, it reduces blood glucose levels. The compound shows PDE10A1 enzyme inhibitory activity (IC50: 7.43 μM) and displays weak hERG inhibition. Naperiglipron has potential applications in type II diabetes mellitus (T2DM) and obesity studies.
CAS Number
2572566-11-9
Synonyms
LY3549492
Molecular Formula
C33H26F2N4O4

Alternative Products

CatalogName
GTR19273147-01Naperiglipron

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