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BBI-2779

CAT: 0957-E5832-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E5832-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BBI-2779 is a potent, selective, and orally active inhibitor of CHK1 with an IC50 of 0.3 nM. It preferentially kills cancer cells containing extrachromosomal DNA (ecDNA) by inducing replication stress and cell death. In gastric cancer models with FGFR2 gene amplification on ecDNA, BBI-2779 suppresses tumor growth and prevents drug resistance.
CAS Number
2871057-47-3
Target
Chk
Activity
Cell Cycle
Molecular Formula
C19H19N7O2

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