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BMS-986408

CAT: 0957-E4747Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E4747Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-986408 is a first-in-class dual inhibitor of DGKα and DGKζ, exhibiting IC50 values of 0.0003 μM and 0.002 μM for DGKα and DGKζ lipid kinase activity, respectively. It potentiates T cell–receptor signaling and T-cell activation, enhancing the effectiveness of both PD-1 and CAR T-cell therapy in preclinical models.
CAS Number
2618418-12-3
Molecular Formula
C27H31F3N6O

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