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TBK1/IKKε-IN-5

CAT: 0957-S8922-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8922-01Size:5 mg
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Description
TBK1/IKKε-IN-5 (compound 1) is a dual inhibitor of TANK-binding kinase 1 (TBK1) and IκB kinase-ε (IKKε/IKK-i) with IC50 of 1.0 nM and 5.6 nM for TBK1 and IKKε, respectively. TBK1/IKKε inhibition enhances response to PD-1 blockade, which effectively predicts tumor response in vivo.
CAS Number
1893397-65-3
Synonyms
Compound 1
Target
IκB/IKK
Activity
NF-κB
Molecular Formula
C28H31N7O3
Storage Conditions
3 years -20°C powder

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Alternative Products

CatalogName
C13785-01TBK1/IKKε-IN-5
A18400-100TBK1/IKKε -IN-5 100mg
A18400-200TBK1/IKKε -IN-5 200mg
A18400-25TBK1/IKKε -IN-5 25mg
A18400-50TBK1/IKKε -IN-5 50mg
A18400-10TBK1/IKKε -IN-5 10mg
A18400-5TBK1/IKKε -IN-5 5mg
A18400-1TBK1/IKKε -IN-5 1mg
HY-U00457TBK1/IKKε-IN-1
HY-122706TBK1/IKKε-IN-3

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