Products for Research Use Only

TAS0728

CAT: 0957-S8833-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-S8833-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TAS0728 (TPC 107) is a potent, selective, orally active, irreversible and covalent-binding inhibitor of HER2 (human epidermal growth factor receptor 2) with IC50 of 13 nM. TAS0728 inihibits BMX, HER4, BLK, EGFR, JAK3, SLK, LOK and human HER2 with IC50 of 4.9 nM, 8.5 nM, 31 nM, 65 nM, 33 nM, 25 nM, 86 nM and 36 nM, respectively. TAS0728 shows antitumor activity.
CAS Number
2088323-16-2
Synonyms
TPC 107
Target
HER2
Activity
Protein Tyrosine Kinase
Molecular Formula
C26H32N8O3
Storage Conditions
3 years -20°C powder