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AZD3229

CAT: 0957-S8780-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0957-S8780-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD3229 is a potent, pan-Kit (c-Kit) mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant Kit (c-Kit) driven Ba/F3 cell lines (GI50=1-50 nM), with good margin to KDR-driven effects. It also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V) .
CAS Number
2248003-60-1
Target
C-Kit
Activity
Protein Tyrosine Kinase
Molecular Formula
C24H26FN7O3
Storage Conditions
3 years -20°C powder