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VU661013

CAT: 0957-S8758-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8758-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU661013 is a novel, potent, selective MCL1 inhibitor with Ki of 97 ± 30 pM of human MCL-1 in a TR-FRET assay. However, VU661013 does not significantly inhibit BCL-xL or BCL-2 with Ki > 40 μM or = 0.73 μM. VU661013 de-stabilizes BIM/MCL-1 association, leads to apoptosis in AML.
CAS Number
2131184-57-9
Target
Bcl-2
Activity
Apoptosis
Molecular Formula
C39H39Cl2N5O4
Storage Conditions
3 years -20°C powder

Alternative Products

CatalogName
A8783-5VU661013
A18363-50VU661013 50mg
A18363-25VU661013 25mg
A18363-100VU661013 100mg
A18363-10VU661013 10mg
A18363-5VU661013 5mg
A18363-1VU661013 1mg
A18363-10mM-DVU661013 10mM * 1mL in DMSO

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