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PLX51107

CAT: 0957-S8739-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8739-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PLX51107 is as a novel BET inhibitor with modest preference for bromodomain-1 (BD1) versus bromodomain-2 (BD2) within each BET protein (Kd = 1.6, 2.1, 1.7, and 5 nM for BD1 and 5.9, 6.2, 6.1 and 120 nM for BD2 of BRD2, BRD3, BRD4, and BRDT, respectively. Among non-BET proteins, PLX51107 shows significant interactions only with the bromodomains of CBP and EP300 (p300) (Kd in the 100 nM range) .
CAS Number
1627929-55-8
Target
Epigenetic Reader Domain
Activity
Epigenetics
Molecular Formula
C26H22N4O3
Storage Conditions
3 years -20°C powder