Products for Research Use Only
RegisterLogin

Verinurad (RDEA3170)

CAT: 0957-S8736-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-S8736-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Verinurad (RDEA3170) is a high-affinity inhibitor of the URAT1 transporter with an IC50 of 25 nM for inhibiting transport activity of human URAT1. It inhibits the related URAT1 homologs OAT4 and OAT1 with approximately 200-fold lower affinity compared to URAT1 with IC50 values of 5.9 μM and 4.6 μM, respectively.
CAS Number
1352792-74-5
Target
OAT
Activity
Transmembrane Transporters
Molecular Formula
C20H16N2O2S
Storage Conditions
3 years -20°C powder

Chemical Information

Verinurad

Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia, and Gout and Asymptomatic Hyperuricemia.

CAS Number1352792-74-5
PubChem CID54767229
IUPAC Name2-[[3-(4-cyanonaphthalen-1-yl)-4-pyridinyl]sulfanyl]-2-methylpropanoic acid
Molecular FormulaC20H16N2O2S
Molecular Weight348.4
XLogP4.1
Topological Polar Surface Area99.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count25
Formal Charge0
Complexity541
SMILES
CC(C)(C(=O)O)SC1=C(C=NC=C1)C2=CC=C(C3=CC=CC=C32)C#N
InChI
InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-18-9-10-22-12-17(18)16-8-7-13(11-21)14-5-3-4-6-15(14)16/h3-10,12H,1-2H3,(H,23,24)
InChIKey
YYBOLPLTQDKXPM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Verinurad
CAS: 1352792-74-5
CID: 54767229
Formula: C20H16N2O2S
MW: 348.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight348.4
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass348.09324893
Monoisotopic Mass348.09324893
Topological Polar Surface Area99.3 Ų
Heavy Atom Count25
Formal Charge0
Complexity541
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
C13628-25mgVerinurad (RDEA3170)
326684Verinurad
A21107-25Verinurad 25mg
A21107-10Verinurad 10mg
HY-16733R-01Verinurad (Standard)
A21107-5Verinurad 5mg
A21107-100Verinurad 100mg
A21107-50Verinurad 50mg
A21107-2Verinurad 2mg
TRC-V125020-25MGVerinurad-d6

Popular Products