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Inavolisib (GDC-0077)

CAT: 0957-S8668-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8668-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Inavolisib (GDC-0077, RG6114, RO-7113755) is a potent selective inhibitor of PI3K alpha (PI3Kα) with an IC50 of 0.038 nM. GDC-0077 is >300-fold more selective for PI3K alpha over the other class I PI3K isoforms (beta, delta, and gamma) and >2000-fold more selective over PIK family members. GDC-0077 binds to the ATP binding site of PI3K and inhibits the phosphorylation of PIP2 to PIP3.
CAS Number
2060571-02-8
Synonyms
RG6114, RO-7113755
Target
PI3K
Activity
PI3K/Akt/mTOR
Molecular Formula
C18H19F2N5O4
Storage Conditions
3 years -20°C powder

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Alternative Products

CatalogName
C13576-25mgInavolisib (GDC-0077)
A19494-100Inavolisib (GDC-0077, RG6114) 100mg
A19494-50Inavolisib (GDC-0077, RG6114) 50mg
A19494-5Inavolisib (GDC-0077, RG6114) 5mg
A19494-25Inavolisib (GDC-0077, RG6114) 25mg
A19494-10Inavolisib (GDC-0077, RG6114) 10mg
A19494-1Inavolisib (GDC-0077, RG6114) 1mg
A19494-10mM-DInavolisib (GDC-0077, RG6114) 10mM * 1mL in DMSO
KHD57102-01GDC-0077
HY-101562-01Inavolisib

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