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PHF21A Polyclonal Antibody

CAT: 0498-bs-11452RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-11452RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.
Synonyms
BHC80a; BM-006; BRAF35-HDAC complex protein BHC80; BRAF35-HDAC complex protein BHC80; BRAF35-HDAC complex protein BHC80; BRAF35/HDAC2 complex 80 kDa; KIAA1696; PF21A_HUMAN; PHD finger protein 21A; PHF21A.
Gene ID
51317
Cellular Locus
Nucleus
Host
Rabbit
Immunogen
351-450/680
Target
PHF21A
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human PHF21A
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
51317
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit

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