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Rogaratinib

CAT: 0957-S8547-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-S8547-01Size:1 mg
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Description
Rogaratinib (BAY-1163877) is a highly potent and selective small molecule inhibitor of pan‐FGFR kinase activity, which specifically inhibits FGFR1, 2, 3 and 4 with an IC50 values of 1.8 nM, <1 nM, 9.2 nM and 1.2 nM respectively. It demonstrates robust efficacy in cancers with altered FGFR mRNA expression.
CAS Number
1443530-05-9
Synonyms
BAY-1163877
Target
FGFR
Activity
Protein Tyrosine Kinase
Molecular Formula
C23H26N6O3S