RegisterLogin

AASS Polyclonal Antibody

CAT: 0498-bs-11391RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-11391RSize:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Alpha-aminoadipic semialdehyde synthase (AASS), also designated lysine ketoglutarate reductase (LKR) or saccharopine dehydrogenase (SDH), is a 926 amino acid protein that exists as a homodimer in the mitochondria. AASS acts as a bifunctional enzyme containing the lysine alpha-ketoglutarate reductase (LKR) and saccharopine dehydrogenase activities that catalyzes the first two steps in lysine degradation. It is widely expressed with highest expression in liver and transcription of the AASS gene is induced upon starvation. Mutations in the gene encoding AASS result in various forms familial hyperlysinemias (FH), autosomal recessive disorders characterized by hyperlysinemia, lysinuria, and variable saccharopinuria. However, no adverse mental or physical effects have been found in patients with hyperlysinemia.
Synonyms
Alpha aminoadipic semialdehyde synthase mitochondrial; LKR/SDH; LKRSDH; LORSDH; Lysine ketoglutarate reductase; Saccharopine dehydrogenase; AASS_HUMAN.
Gene ID
10157
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
878-926/926
Target
AASS
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human LKRSDH
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
10157
Predicted Cross Reactivity
Human, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit

Related Products

CatalogName
bs-102638P-01Recombinant Human AASS Protein, N-His
bs-18692RMATH5 Polyclonal Antibody
bs-1870R-01PEG3 Polyclonal Antibody
bs-18767RMED28 Polyclonal Antibody
bs-1879R-01PSAP Polyclonal Antibody
bs-1881RSecurin Polyclonal Antibody
bs-1882RMRas Polyclonal Antibody
bs-18846RRRNAD1 Polyclonal Antibody
bs-18862RRRS1 Polyclonal Antibody
bs-18877RRSPO3 Polyclonal Antibody

Alternative Products

CatalogName
UB-GEN-2391AASS Polyclonal Antibody
TA343313AASS Rabbit Polyclonal Antibody
PHJ74401Anti-AASS Polyclonal Antibody
NBP1-82832Rabbit Polyclonal AASS Antibody

Popular Products