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Tucatinib

CAT: 0957-S8362-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S8362-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tucatinib (Irbinitinib, ONT-380, ARRY-380) is an oral, potent, selective, reversible and ATP-competitive small-molecule inhibitor of ErbB-2 (also called HER2) with IC50s of 8 nM and 7 nM for ErbB-2 and p95 HER2, respectively in cell-based assays, showing ~500-fold selective for HER2 vs EGFR. It has potential antineoplastic activity.
CAS Number
937263-43-9
Synonyms
Irbinitinib, ONT-380, ARRY-380
Target
HER2
Activity
Protein Tyrosine Kinase
Molecular Formula
C26H24N8O2
Storage Conditions
2 years -80 in solvent

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