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PF-06409577

CAT: 0957-S8335-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S8335-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-06409577 is an orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms.
CAS Number
1467057-23-3
Target
AMPK
Activity
PI3K/Akt/mTOR
Molecular Formula
C19H16ClNO3
Storage Conditions
2 years -80 in solvent