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Bardoxolone Methyl

CAT: 0957-S8078-01Size: 25 mgDry Ice: YesHazardous: No
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CAT#:0957-S8078-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bardoxolone Methyl (RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me) is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor. Bardoxolone Methyl abrogates ferroptosis. Bardoxolone methyl induces apoptosis and autophagy in cancer cells.
CAS Number
218600-53-4
Synonyms
RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me
Target
IκB/IKK
Activity
NF-κB
Molecular Formula
C32H43NO4
Storage Conditions
2 years -80 in solvent