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Thapsigargin

CAT: 0957-S7895-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-S7895-01Size:1 mg
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Description
Thapsigargin is a potent, non-competitive inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) with IC50 of 0.353 nM or 0.448 nM for the carbachol-evoked [Ca2+]i-transients with or without a KCl-prestimulation. Thapsigargin induces cell apoptosis. Thapsigargin is extracted from a plant, Thapsia garganica.
CAS Number
67526-95-8
Target
ATPase
Activity
Transmembrane Transporters
Molecular Formula
C34H50O12
Storage Conditions
3 years -20°C powder

Alternative Products

CatalogName
TBZ1976Thapsigargin

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