Products for Research Use Only

OTS964

CAT: 0957-S7648-01Size: 5 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0957-S7648-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
OTS964 is a potent TOPK inhibitor with high affinity and selectivity and IC50 value is 28 nM. OTS964 is also a potent inhibitor of the cyclin-dependent kinase CDK11 with Kd of 40 nM. OTS964 treatment activates autophagy in glioma cells and induces apoptosis of human lung cancer cells in mouse xenografts.
CAS Number
1338545-07-5
Target
TOPK
Activity
MAPK
Molecular Formula
C23H24N2O2S.HCl
Storage Conditions
2 years -80 in solvent