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Lorlatinib (PF-6463922)

CAT: 0957-S7536-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S7536-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lorlatinib (PF-6463922) is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively. PF-06463922 induces apoptosis. Phase 1.
CAS Number
1454846-35-5
Target
ALK
Activity
Protein Tyrosine Kinase
Molecular Formula
C21H19FN6O2
Storage Conditions
2 years -80 in solvent