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Rocaglamide

CAT: 0957-S7428-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-S7428-01Size:1 mg
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Description
Rocaglamide (Roc-A), isolated from Aglaia species, is a potent inhibitor of heat shock factor 1 (HSF1) activation with IC50 of ~50 nM for HSF1. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also inhibits NF-κB activity. Rocaglamide exhibits anti-tumor activity.
CAS Number
84573-16-0
Synonyms
Roc-A
Target
HSP (HSP90)
Activity
Cytoskeletal Signaling
Molecular Formula
C29H31NO7
Storage Conditions
3 years -20°C powder

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