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KN-62

CAT: 0957-S7422-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S7422-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KN-62 is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.9 μM; also a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM) . It is selective for CaMKII relative to PKA, PKC and MLCK, but inhibits CaMKI and CaMKIV equally well, The Ki value of KN-62 for CaMK V is 0.8 μM.
CAS Number
127191-97-3
Target
CaMK
Activity
Neuronal Signaling
Molecular Formula
C38H35N5O6S2
Storage Conditions
2 years -80 in solvent

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HY-13290-01KN-62
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