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Sorafenib

CAT: 0957-S7397-01Size: 20 mgDry Ice: YesHazardous: No
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CAT#:0957-S7397-01Size:20 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sorafenib is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.
CAS Number
284461-73-0
Synonyms
NSC-724772, BAY 43-9006
Target
Raf
Activity
MAPK
Molecular Formula
C21H16ClF3N4O3
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
GP6971-100mgSorafenib

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