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URMC-099

CAT: 0957-S7343-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S7343-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM. URMC-099 also inhibits ABL1 with IC50 of 6.8 nM. URMC-099 induces autophagy.
CAS Number
1229582-33-5
Target
LRRK2
Activity
Autophagy
Molecular Formula
C27H27N5
Storage Conditions
2 years -80 in solvent

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