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Mdivi-1

CAT: 0957-S7162-02Size: 10 mm/ 1 mLDry Ice: YesHazardous: No
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CAT#:0957-S7162-02Size:10 mm/ 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Mdivi-1 attenuates mitophagy and enhances apoptosis.
CAS Number
338967-87-6
Synonyms
Mitochondrial division inhibitor 1
Target
Dynamin
Activity
Cytoskeletal Signaling
Molecular Formula
C15H10Cl2N2O2S
Storage Conditions
2 years -80 in solvent

Chemical Information

3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone

Mdivi-1 is a member of quinazolines.

CAS Number338967-87-6
PubChem CID3825829
IUPAC Name3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanylidene-1H-quinazolin-4-one
Molecular FormulaC15H10Cl2N2O2S
Molecular Weight353.2
XLogP4
Topological Polar Surface Area73.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count22
Formal Charge0
Complexity465
SMILES
COC1=C(C=C(C(=C1)N2C(=O)C3=CC=CC=C3NC2=S)Cl)Cl
InChI
InChI=1S/C15H10Cl2N2O2S/c1-21-13-7-12(9(16)6-10(13)17)19-14(20)8-4-2-3-5-11(8)18-15(19)22/h2-7H,1H3,(H,18,22)
InChIKey
NZJKEVWTYMOYOR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone
CAS: 338967-87-6
CID: 3825829
Formula: C15H10Cl2N2O2S
MW: 353.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight353.2
XLogP34
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass351.9840041
Monoisotopic Mass351.9840041
Topological Polar Surface Area73.7 Ų
Heavy Atom Count22
Formal Charge0
Complexity465
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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