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APY29

CAT: 0957-S6623-02Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0957-S6623-02Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
APY29 is a type I kinase inhibitor of IRE1α that binds to the ATP-binding site on IRE1α and inhibits its autophosphorylation (IC50 = 280 nM) and enhances its RNase function (EC50 = 460 nM) .
CAS Number
1216665-49-4
Target
IRE1
Activity
ER stress & UPR
Molecular Formula
C17H16N8
Storage Conditions
3 years -20°C powder