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CVT-313

CAT: 0957-S6537-02Size: 10 mm/ 1 mLDry Ice: NoHazardous: No
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CAT#:0957-S6537-02Size:10 mm/ 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CVT-313 is a potent CDK2 inhibitor with an IC50 of 0.5 microM in vitro. It has no effect on other, nonrelated ATP-dependent serine/threonine kinases.
CAS Number
199986-75-9
Target
CDK
Activity
Cell Cycle
Molecular Formula
C20H28N6O3
Storage Conditions
3 years -20°C powder

Chemical Information

Cvt-313

a potent inhibitor of CDK2 that prevents neointimal proliferation; structure given in first source

CAS Number199986-75-9
PubChem CID6918386
IUPAC Name2-[2-hydroxyethyl-[6-[(4-methoxyphenyl)methylamino]-9-propan-2-ylpurin-2-yl]amino]ethanol
Molecular FormulaC20H28N6O3
Molecular Weight400.5
XLogP1.6
Topological Polar Surface Area109
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count10
Heavy Atom Count29
Formal Charge0
Complexity471
SMILES
CC(C)N1C=NC2=C(N=C(N=C21)N(CCO)CCO)NCC3=CC=C(C=C3)OC
InChI
InChI=1S/C20H28N6O3/c1-14(2)26-13-22-17-18(21-12-15-4-6-16(29-3)7-5-15)23-20(24-19(17)26)25(8-10-27)9-11-28/h4-7,13-14,27-28H,8-12H2,1-3H3,(H,21,23,24)
InChIKey
NQVIIUBWMBHLOZ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Cvt-313
CAS: 199986-75-9
CID: 6918386
Formula: C20H28N6O3
MW: 400.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight400.5
XLogP31.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count10
Exact Mass400.22228878
Monoisotopic Mass400.22228878
Topological Polar Surface Area109 Ų
Heavy Atom Count29
Formal Charge0
Complexity471
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
A3336-200CVT-313
TRC-C856005-100MGCVT 313

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