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Amitriptyline

CAT: 0957-S5947Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0957-S5947Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.
CAS Number
50-48-6
Synonyms
MK-230, N-750, Ro41575
Target
5-HT Receptor
Activity
Neuronal Signaling
Molecular Formula
C20H23N
Storage Conditions
2 years -20°C liquid

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