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Cabozantinib malate

CAT: 0957-S4001-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S4001-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cabozantinib malate (XL184) is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret (c-Ret), Kit (c-Kit), Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib malate (XL184) induces apoptosis.
CAS Number
1140909-48-3
Synonyms
XL184
Target
Axl
Activity
Protein Tyrosine Kinase
Molecular Formula
C28H24FN3O5.C4H6O5
Storage Conditions
2 years -80 in solvent

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