Integrin alpha 2 Polyclonal Antibody

CAT: 0498-bs-10132R-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0498-bs-10132R-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.
Synonyms
ITGA2; Integrin alpha 2; CD49b antigen; BR; CD 49b; CD49 antigen like family member B; CD49b; CD49b; Collagen receptor; DX5 ; Glycoprotein Ia deficiency included; GP Ia; GP Ia deficiency, included; GPIa; HPA 5 included; HPA5 included; Platelet alloantigen Bra, included; Platelet antigen Br; Platelet glycoprotein GPIa; Platelet glycoprotein Ia; Platelet glycoprotein Ia/Iia; Platelet membrane glycoprotein Ia; Platelet receptor for collagen, deficiency of, included; Very late activation protein 2 receptor alpha 2 subunit; VLA 2 alpha chain; VLA 2; VLA 2 subunit alpha; VLA2 alpha chain; ITA2_HUMAN.
Gene ID
3673
Swiss Prot
P17301
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
801-900/1181
Target
Integrin alpha 2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Integrin alpha 2/CD49b
Applications
WB, ELISA
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
3673
Predicted Cross Reactivity
Mouse, Rat, Pig, Horse, Rabbit

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