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UCB-9260

CAT: 0957-S3231-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S3231-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13 nM. UCB-9260 also inhibits NF-κB with IC50 of 202 nM after TNF stimulation.
CAS Number
1515888-53-5
Target
TNF-alpha
Activity
Apoptosis
Molecular Formula
C26H25N5O
Storage Conditions
3 years -20°C powder